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1.
Arq. bras. neurocir ; 40(3): 222-228, 15/09/2021.
Artículo en Inglés | LILACS | ID: biblio-1362108

RESUMEN

Introduction The side-to-end hypoglossal-facial anastomosis (HFA) technique is an excellent alternative technique to the classic end-terminal anastomosis, because itmay decrease the symptoms resulting from hypoglossal-nerve transection. Methods Patients with facial nerve palsy (House-Brackmann [HB] grade VI) requiring facial reconstruction from 2014 to 2017were retrospectively included in the study. Results In total, 12 cases were identified, with a mean follow-up of 3 years. The causes of facial paralysis were due to resection of posterior-fossa tumors and trauma. There was improvement in 91.6% of the patients (11/12) after the HFA. The rate of improvement according to the HB grade was as follows: HB III - 58.3%; HB IV - 16.6%; and HB II - 16.6%. The first signs of improvement were observed in the patients with the shortest time between the paralysis and the anastomosis surgery (3.5months versus 8.5 months; p » 0.011). The patients with HB II and III had a shorter time between the diagnosis and the anastomosis surgery (mean: 5.22 months), while the patients with HB IV and VI had a longer time of paresis (mean: 9.5 months; p » 0.099). We did not observe lingual atrophy or changes in swallowing. Discussion and Conclusion Hypoglossal-facial anastomosis with the terminolateral technique has good results and low morbidity in relation to tongue motility and swallowing problems. The HB grade and recovery appear to be better in patients operated on with a shorter paralysis time.


Asunto(s)
Anastomosis Quirúrgica/métodos , Anastomosis Quirúrgica/rehabilitación , Nervio Facial/cirugía , Parálisis Facial/rehabilitación , Nervio Hipogloso/cirugía , Registros Médicos , Interpretación Estadística de Datos , Resultado del Tratamiento , Estadísticas no Paramétricas , Procedimientos de Cirugía Plástica/rehabilitación , Recuperación de la Función , Parálisis Facial/cirugía , Parálisis Facial/etiología
2.
Asian J Neurosurg ; 16(2): 243-248, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34268146

RESUMEN

INTRODUCTION: Intramedullary spinal cord tumors (IMSCT) account for about 2%-4% of all central nervous system tumors. Surgical resection is the main treatment step, but might cause damage to functional tissues. Intraoperative neuromonitoring (IONM) is an adopted measure to decrease surgical complications. Below, we describe the results of IMSCT submitted to surgery under IONM at a tertiary institution. METHODS: The sample consisted of consecutive patients with IMSCT admitted to the Neurological Institute of Curitiba from January 2007 to November 2016. A total of 47 patients were surgically treated. Twenty-three were male (48.9%) and 24 were female (51.1%). The mean age was 42.77 years. The mean follow-up time was 42.7 months. RESULTS: Neurological status improved in 29 patients (62%), stable in 6 (13%), and worse in 12 (25%). Patients who presented with motor symptoms at initial diagnosis had a worse outcome compared to patients with sensory impairment and pain (P = 0.026). Patients with a change in electromyography had worse neurological outcomes compared to patients who did not show changes in monitoring (P = 0.017). DISCUSSION AND CONCLUSION: No prospective randomized high evidence study has been performed to date to compare clinical evolution after surgery with or without monitoring. In our sample, surgical resection was well succeeded mainly in oligosymptomatic patients with low preoperative McCormick classification and no worsening of IONM during surgery. We believe that microsurgical resection of IMSCT with simultaneous IONM is the gold standard treatment and achieved with good results.

3.
Br J Neurosurg ; : 1-6, 2021 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-33517784

RESUMEN

INTRODUCTION: Epidermoid cysts (EC) are lesions developing from neuroectodermal epithelial cells. They represent 1-2% of all intracranial tumors and are usually found in cerebellopontine angle and parasellar regions. To the best of our knowledge, only 27 cases have been reported of EC in sellar and suprasellar region. In 12 cases out of the 27, surgery was done by craniotomy means. The 7 most recent manuscripts (with 15 patients described) share in common the use of endoscopic endonasal approach (EEA) to perform surgical removal. RESULTS: In this paper, we report the safe removal of epidermoid cysts arising from the pituitary using an EEA in two patients, which should be the sixth such description in literature. In both cases, resection and evolution was favourable. DISCUSSION: Surgical resection is the treatment standard for epidermoid cysts, with total resection including the cyst wall to prevent recurrence when possible. The degree of resection obtained is limited by adherence to nearby neural and vascular structures. The advent of EEA approaches has allowed safe maximal resection especially in midline lesions nearby sellar and suprasellar compartiments.

4.
Neurosurg Rev ; 44(2): 1071-1081, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-32281018

RESUMEN

Lumbar disc herniation (LDH) is a relatively common pathology usually presenting with unilateral radiculopathy ipsilateral to the disc herniation. Some patients can present with contralateral radicular symptoms. The objective of this article is to review the current literature on lumbar disc herniations with contralateral radiculopathy regarding its pathophysiology and surgical strategies. A systematic review of the literature on LDH with contralateral radiculopathy was performed using MEDLINE (via PubMed) using MeSH terms. This review was done following recommendations of PRISMA statement and PICOT strategy of search. Initial electronic search identified 126 papers. Finally, 18 articles were reviewed. None of the included papers was described as comparative. Pathophysiological processes underlying contralateral pain may include prominent spondylotic changes and the accompanying stenosis; hypertrophic yellow ligament; dural attachments along the posterior longitudinal ligament; nerve root traction forces; and friction radiculitis, migrated epidural fat, nerve root anomaly, and venous congestion inside the vertebral canal. In our pooled analysis, 11 patients reported were treated by bilateral approach with 100% of clinical success and no complications. Eight patients were treated by unilateral approach ipsilateral to pain with 100% of clinical success and no complications. Forty-eight patients were treated by unilateral approach ipsilateral to herniation with 100% of clinical success and no complications. Pathophysiology underlying contralateral pain in LDH is probably multifactorial. There is not enough scientific evidence to define the best surgical approach for patients with LDH and contralateral pain.


Asunto(s)
Desplazamiento del Disco Intervertebral/fisiopatología , Desplazamiento del Disco Intervertebral/cirugía , Vértebras Lumbares/cirugía , Procedimientos Neuroquirúrgicos/métodos , Radiculopatía/fisiopatología , Radiculopatía/cirugía , Femenino , Humanos , Degeneración del Disco Intervertebral/epidemiología , Degeneración del Disco Intervertebral/fisiopatología , Degeneración del Disco Intervertebral/cirugía , Desplazamiento del Disco Intervertebral/epidemiología , Masculino , Procedimientos Neuroquirúrgicos/tendencias , Estudios Observacionales como Asunto/métodos , Dolor/epidemiología , Dolor/fisiopatología , Dolor/cirugía , Radiculopatía/epidemiología
5.
World Neurosurg ; 138: 125-128, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-32147548

RESUMEN

BACKGROUND: Hemichorea may point to a structural lesion in the contralateral basal ganglia with a large list of possible causes. Cavernous angioma may be rarely a possible cause for acute appearance of this movement disorder. CASE DESCRIPTION: We present a rare case of a 32-year-old female patient with hemichorea caused by a cavernoma (or cavernous angioma) in the contralateral insula and putamen with complete improvement of symptoms with surgical resection of the lesion. CONCLUSIONS: We believe that surgical resection of basal ganglia cavernomas may be feasible with minor risks and resolution of clinical symptoms in the immediate postoperative period.


Asunto(s)
Neoplasias Encefálicas/complicaciones , Neoplasias Encefálicas/cirugía , Hemangioma Cavernoso/complicaciones , Hemangioma Cavernoso/cirugía , Paresia/etiología , Paresia/cirugía , Adulto , Ganglios Basales/diagnóstico por imagen , Corteza Cerebral/diagnóstico por imagen , Femenino , Humanos , Imagen por Resonancia Magnética , Procedimientos Neuroquirúrgicos/métodos , Complicaciones Posoperatorias/terapia , Putamen/diagnóstico por imagen
6.
World Neurosurg ; 135: e488-e493, 2020 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-31843724

RESUMEN

BACKGROUND: Vestibular schwannoma (VS) is the most common benign tumor originating in the cerebellopontine angle. In most cases, tumors tend to grow and deserve proper treatment. Sometimes they stabilize, and rarely they decrease in size spontaneously. METHODS: We evaluated retrospectively the images of patients with spontaneous tumor regression. We describe the common neuroimage findings of patients with spontaneous tumoral regression. RESULTS: Four patients with diagnosis of VS were followed with magnetic resonance imaging (MRI). There were some relevant features in MRI: a heterogeneous contrast enhancement in the outer layer of the tumor and presence of a cerebrospinal fluid column between the tumor and the entrance of the internal auditory canal. The percentage of tumor diameter reduction ranged from 20% to 40%. CONCLUSIONS: Some MRI features may demonstrate a spontaneous involution of VS and may be closely followed in asymptomatic or oligosymptomatic patients.


Asunto(s)
Neoplasias Cerebelosas/patología , Ángulo Pontocerebeloso/patología , Neuroma Acústico/patología , Adulto , Anciano , Neoplasias Cerebelosas/complicaciones , Femenino , Pérdida Auditiva/etiología , Pérdida Auditiva/patología , Humanos , Imagen por Resonancia Magnética/métodos , Masculino , Persona de Mediana Edad , Regresión Neoplásica Espontánea/patología , Neuroma Acústico/complicaciones , Estudios Retrospectivos , Acúfeno/etiología , Acúfeno/patología
7.
Acta Neurochir (Wien) ; 160(10): 1905-1908, 2018 10.
Artículo en Inglés | MEDLINE | ID: mdl-30091052

RESUMEN

BACKGROUND: According to our research, just few studies described 5-Aminolevulinic acid (5-ALA) use for spinal injuries resection. 5-ALA is known to be especially useful in certain spinal tumor entities such as meningiomas, ependymomas, hemangiopericytomas, and metastasis of central nervous system primary tumors. In contrast, 5-ALA has limited value in other histopathological tumoral entities, as neurinomas and carcinoma metastasis. METHOD: We describe a microsurgical resection of a spinal cord melanoma through fluorescence-guided technique using 5-ALA in a 36-year-old man. RESULTS: Strong 5-ALA tumor enhancement was evidenced, resulting in gross-total resection. CONCLUSION: To our knowledge, this is the first case of nonglial intramedullary metastasis with 5-ALA positive staining. We believe that this tool, 5-ALA, could aid in the resection, identification, and differentiation of medullary metastasis.


Asunto(s)
Neoplasias Encefálicas/cirugía , Ependimoma/cirugía , Melanoma/cirugía , Neoplasias Meníngeas/cirugía , Meningioma/cirugía , Neoplasias de la Médula Espinal/cirugía , Cirugía Asistida por Computador/métodos , Adulto , Ácido Aminolevulínico , Femenino , Colorantes Fluorescentes , Humanos , Masculino
8.
Turk Neurosurg ; 28(4): 689-690, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-27858382

RESUMEN

MATERIAL AND METHODS: A case of 60-year-old woman with idiopathic syringomyelia and progressive myelopathy by dorsal arachnoid web is discussed. One focal indentation along the dorsal surface of the spinal cord at the T3 vertebral body level revealed the scalpel sign, a radiologic entity diagnostic of a dorsal thoracic arachnoid web. RESULTS: T2-T3 laminectomy for the resection of dorsal arachnoid band was performed. Careful sectioning of the web resulted in visual apparent relief of the compression and good functional recovery. CONCLUSION: In patients with presumed idiopathic syringomyelia, imaging studies should be closely inspected for the presence of transverse arachnoid web. This extramedullary transverse band of arachnoid tissue extends to dorsal surface of the spinal cord, resulting in mass effect and dorsal indentation, known as scalpel sign because of its apparent resemblance to a scalpel on sagittal imaging. Early diagnosis with early intervention may benefit greatly patients. Surgical resection of transverse arachnoid web is a minimally invasive procedure with low morbidity, and can result in resolution of syringomyelia and improvement in neurological function.

9.
Rev Assoc Med Bras (1992) ; 63(4): 307-310, 2017 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-28614531

RESUMEN

Osteogenesis imperfecta (OI) is a bone disorder that can lead to skull base deformities such as basilar invagination, which can cause compression of cranial nerves, including the trigeminal nerve. Trigeminal neuralgia in such cases remains a challenge, given distorted anatomy and deformities. We present an alternative option, consisting in cannulation of the foramen ovale and classical percutaneous treatment. Percutaneous balloon microcompression was performed in a 28 year-old woman with OI and severe trigeminal neuralgia using computed tomography (CT) and radiographic-guided cannulation of the Gasserian ganglion without neuronavigation or stereotactic devices. The patient developed hypoesthesia on the left V1, V2 and V3 segments with good pain control. This alternative technique with a CT-guided puncture, using angiosuite without the need of any Mayfield clamp, neuronavigation systems, frame or frameless stereotactic devices can be a useful, safe and efficient alternative for patients with trigeminal neuralgia with other bone deforming diseases that severely affect the skull base.


Asunto(s)
Cateterismo/métodos , Foramen Oval/cirugía , Osteogénesis Imperfecta/cirugía , Neuralgia del Trigémino/cirugía , Adulto , Angiografía , Femenino , Foramen Oval/diagnóstico por imagen , Humanos , Osteogénesis Imperfecta/diagnóstico por imagen , Reproducibilidad de los Resultados , Tomografía Computarizada por Rayos X , Resultado del Tratamiento , Neuralgia del Trigémino/diagnóstico por imagen
10.
Rev. Assoc. Med. Bras. (1992) ; 63(4): 307-310, Apr. 2017. graf
Artículo en Inglés | LILACS | ID: biblio-842547

RESUMEN

Summary Osteogenesis imperfecta (OI) is a bone disorder that can lead to skull base deformities such as basilar invagination, which can cause compression of cranial nerves, including the trigeminal nerve. Trigeminal neuralgia in such cases remains a challenge, given distorted anatomy and deformities. We present an alternative option, consisting in cannulation of the foramen ovale and classical percutaneous treatment. Percutaneous balloon microcompression was performed in a 28 year-old woman with OI and severe trigeminal neuralgia using computed tomography (CT) and radiographic-guided cannulation of the Gasserian ganglion without neuronavigation or stereotactic devices. The patient developed hypoesthesia on the left V1, V2 and V3 segments with good pain control. This alternative technique with a CT-guided puncture, using angiosuite without the need of any Mayfield clamp, neuronavigation systems, frame or frameless stereotactic devices can be a useful, safe and efficient alternative for patients with trigeminal neuralgia with other bone deforming diseases that severely affect the skull base.


Resumo Osteogênese imperfeita (OI) é uma doença óssea que pode levar a deformidades de base de crânio, como invaginação basilar que pode provocar compressão de nervo craniano, incluindo o nervo trigêmeo. Nestes casos, a neuralgia do trigêmeo permanece como um desafio, pela anatomia distorcida e pelas deformidades. Apresentamos uma alternativa que consiste na canulação do forame oval e no tratamento percutâneo clássico. A microcompressão percutânea por balão foi realizada em uma paciente de 28 anos apresentando OI e grave neuralgia do trigêmeo, sendo realizadas tomografia computadorizada (CT) e canulação guiadas do gânglio gasseriano sem neuronavegação ou dispositivos estereotáxicos. A paciente apresentou hipoestesia à esquerda dos segmentos V1, V2 e V3, com bom controle da dor. Essa técnica alternativa com punção orientada por CT utilizando o angiosuite sem a necessidade de qualquer grampo de Mayfield, sistemas de neuronavegação, ou dispositivos com ou sem arcos estereotáxicos, pode ser uma opção útil, segura e eficiente para pacientes com neuralgia do trigêmeo cursando com outras doenças deformativas que afetem a base craniana de modo grave.


Asunto(s)
Humanos , Femenino , Adulto , Osteogénesis Imperfecta/cirugía , Neuralgia del Trigémino/cirugía , Cateterismo/métodos , Foramen Oval/cirugía , Osteogénesis Imperfecta/diagnóstico por imagen , Neuralgia del Trigémino/diagnóstico por imagen , Angiografía , Tomografía Computarizada por Rayos X , Reproducibilidad de los Resultados , Resultado del Tratamiento , Foramen Oval/diagnóstico por imagen
11.
Rev Assoc Med Bras (1992) ; 62(9): 828-830, 2016 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-28001255

RESUMEN

Arteriovenous malformations (AVMs) of the scalp are rare lesions. The clinical picture presents with complaints of increased scalp, scalp disfigurement, pain and neurological symptoms. Its origin can be congenital or traumatic. We present a case of giant scalp AVMs and its management, followed by a brief literature review on the subject. The diagnosis of scalp AVMs is based on physical examination and confirmed by internal and external carotid angiography or computed tomographic angiography (CTA). Surgical excision is especially effective in scalp AVMs, and is the most frequently used treatment modality.


Asunto(s)
Malformaciones Arteriovenosas/diagnóstico por imagen , Malformaciones Arteriovenosas/cirugía , Cuero Cabelludo/irrigación sanguínea , Adulto , Angiografía por Tomografía Computarizada , Humanos , Masculino , Fotograbar , Cuero Cabelludo/anomalías , Cuero Cabelludo/cirugía
12.
Rev Assoc Med Bras (1992) ; 62(8): 721-724, 2016 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-27992010

RESUMEN

According to our research, this is the first case described in the literature of spontaneous intracranial epidural hematoma secondary to the use of Xareltor. Spontaneous intracranial epidural hematomas are rarely described in the literature. They are associated with infectious diseases of the skull, coagulation disorders, vascular malformations of the dura mater and metastasis to the skull. Long-term post-marketing monitoring and independent reports will probably detect the full spectrum of hemorrhagic complications of the use of rivaroxaban.


Asunto(s)
Inhibidores del Factor Xa/efectos adversos , Hematoma Epidural Craneal/inducido químicamente , Rivaroxabán/efectos adversos , Adulto , Hematoma Epidural Craneal/diagnóstico por imagen , Hematoma Epidural Craneal/cirugía , Humanos , Masculino , Riesgo , Tomografía Computarizada por Rayos X
13.
Rev. Assoc. Med. Bras. (1992) ; 62(9): 828-830, Dec. 2016. graf
Artículo en Inglés | LILACS | ID: biblio-829550

RESUMEN

SUMMARY Arteriovenous malformations (AVMs) of the scalp are rare lesions. The clinical picture presents with complaints of increased scalp, scalp disfigurement, pain and neurological symptoms. Its origin can be congenital or traumatic. We present a case of giant scalp AVMs and its management, followed by a brief literature review on the subject. The diagnosis of scalp AVMs is based on physical examination and confirmed by internal and external carotid angiography or computed tomographic angiography (CTA). Surgical excision is especially effective in scalp AVMs, and is the most frequently used treatment modality.


RESUMO Malformações arteriovenosas (MAV) do couro cabeludo são lesões raras. O quadro clínico apresenta-se com queixas de aumento do couro cabeludo, desfiguração do couro cabeludo, dor e sintomas neurológicos. A origem pode ser congênita ou traumática. Apresentamos um caso de MAV gigante de couro cabeludo e o tratamento adotado, seguindo-se uma breve revisão da literatura. O diagnóstico das MAV de couro cabeludo baseia-se no exame físico e é confirmado pela angiografia carótida interna e externa ou angiografia por tomografia computadorizada. A excisão cirúrgica é especialmente eficaz em MAV de couro cabeludo e é a modalidade de tratamento mais frequentemente utilizada.


Asunto(s)
Humanos , Masculino , Adulto , Malformaciones Arteriovenosas/cirugía , Malformaciones Arteriovenosas/diagnóstico por imagen , Cuero Cabelludo/irrigación sanguínea , Cuero Cabelludo/anomalías , Cuero Cabelludo/cirugía , Fotograbar , Angiografía por Tomografía Computarizada
14.
Rev. Assoc. Med. Bras. (1992) ; 62(8): 721-724, Nov. 2016. graf
Artículo en Inglés | LILACS | ID: biblio-829538

RESUMEN

Summary According to our research, this is the first case described in the literature of spontaneous intracranial epidural hematoma secondary to the use of Xareltor. Spontaneous intracranial epidural hematomas are rarely described in the literature. They are associated with infectious diseases of the skull, coagulation disorders, vascular malformations of the dura mater and metastasis to the skull. Long-term post-marketing monitoring and independent reports will probably detect the full spectrum of hemorrhagic complications of the use of rivaroxaban.


Resumo Segundo nossa pesquisa, descrevemos o primeiro caso na literatura de hematoma epidural intracraniano espontâneo secundário ao uso de Xareltor. Hematomas epidurais intracranianos espontâneos raramente são descritos na literatura, sendo comumente associados a doenças infecciosas cranianas, distúrbios de coagulação, malformações vasculares da dura-máter e metástases cranianas. A elaboração de relatórios de monitoramento em longo prazo de pós-comercialização e relatórios independentes provavelmente irá detectar o espectro completo de complicações hemorrágicas do uso desse medicamento.


Asunto(s)
Humanos , Masculino , Adulto , Inhibidores del Factor Xa/efectos adversos , Rivaroxabán/efectos adversos , Hematoma Epidural Craneal/inducido químicamente , Tomografía Computarizada por Rayos X , Riesgo , Hematoma Epidural Craneal/cirugía , Hematoma Epidural Craneal/diagnóstico por imagen
15.
Rev. Assoc. Med. Bras. (1992) ; 59(6): 589-593, nov.-dez. 2013. tab
Artículo en Inglés | LILACS | ID: lil-697390

RESUMEN

OBJECTIVE: To verify the association between depression and headache in young adults, as well as to identify the features of headache associated with depression and the influence of this mood disorder on headache-related disability. METHODS: A cross-sectional study with self-administered questionnaires about headache and depression was conducted at the Universidade de Caxias do Sul. Beck Depression Inventory (BDI) and Migraine Disability Assessment (MIDAS) were used to evaluate depressive symptoms and headache-related disability, respectively. Depression was considered if BDI > 15. RESULTS: A thousand and thirteen young adults were included in the study. A clear relationship was observed between headache and depression among the participants. Multivariate analyses demonstrated that nausea or vomiting related to headache and higher headacherelated disability scores were independent factors associated with depression. Migraine was more associated with depression than the other types of headache. CONCLUSION: The results demonstrate an association between headache and depression. Depressive symptoms are more likely to be found in young adults with more disabling headaches.


OBJETIVO: Verificar a associação entre depressão e cefaleia em adultos jovens, assim como identificar as características da cefaleia relacionadas com depressão e a influência da depressão na incapacidade decorrente da cefaleia. MÉTODOS: Estudo transversal com questionários autoadministrados sobre cefaleia e depressão foi conduzido na Universidade de Caxias do Sul. O Inventário de Depressão de Beck (BDI) e o questionário de avaliação da incapacidade por enxaqueca (MIDAS) foram utilizados para avaliação dos sintomas depressivos e incapacidade, respectivamente. Depressão foi definida como BDI > 15. RESULTADOS: Foram incluídos no estudo 1.013 adultos jovens. Observou-se uma clara relação entre cefaleia e depressão entre os participantes. Análisesmultivariadas demonstraramque náuseas ou vômitos relacionados à cefaleia e incapacidade decorrente da dor foram fatores independentes associados à depressão. Enxaqueca foi mais associada com depressão que os outros tipos de cefaleia. CONCLUSÃO: Os resultados demonstram associação entre cefaleia e depressão. Sintomas depressivos são mais comuns em adultos jovens com cefaleias mais incapacitantes.


Asunto(s)
Adolescente , Adulto , Femenino , Humanos , Masculino , Adulto Joven , Trastorno Depresivo/complicaciones , Cefalea/psicología , Distribución por Edad , Brasil/epidemiología , Estudios Transversales , Trastorno Depresivo/epidemiología , Cefalea/epidemiología , Trastornos Migrañosos/complicaciones , Trastornos Migrañosos/epidemiología , Prevalencia , Encuestas y Cuestionarios
16.
Rev Assoc Med Bras (1992) ; 59(6): 589-93, 2013.
Artículo en Inglés, Portugués | MEDLINE | ID: mdl-24182892

RESUMEN

OBJECTIVE: To verify the association between depression and headache in young adults, as well as to identify the features of headache associated with depression and the influence of this mood disorder on headache-related disability. METHODS: A cross-sectional study with self-administered questionnaires about headache and depression was conducted at the Universidade de Caxias do Sul. Beck Depression Inventory (BDI) and Migraine Disability Assessment (MIDAS) were used to evaluate depressive symptoms and headache-related disability, respectively. Depression was considered if BDI ≥ 15. RESULTS: A thousand and thirteen young adults were included in the study. A clear relationship was observed between headache and depression among the participants. Multivariate analyses demonstrated that nausea or vomiting related to headache and higher headache-related disability scores were independent factors associated with depression. Migraine was more associated with depression than the other types of headache. CONCLUSION: The results demonstrate an association between headache and depression. Depressive symptoms are more likely to be found in young adults with more disabling headaches.


Asunto(s)
Trastorno Depresivo/complicaciones , Cefalea/psicología , Adolescente , Adulto , Distribución por Edad , Brasil/epidemiología , Estudios Transversales , Trastorno Depresivo/epidemiología , Femenino , Cefalea/epidemiología , Humanos , Masculino , Trastornos Migrañosos/complicaciones , Trastornos Migrañosos/epidemiología , Prevalencia , Encuestas y Cuestionarios , Adulto Joven
17.
J. bras. neurocir ; 24(4): 352-349, 2013.
Artículo en Portugués | LILACS | ID: lil-737585

RESUMEN

A neuralgia do trigêmeo é geralmente uma doença de idosos. Raramente, a doença apresenta-se durante a infância. Porisso, procuramos explorar o papel da compressão vascular em pacientes pediátricos com neuralgia do trigêmeo refratária.Apresentamos um caso de compressão venosa relacionado à neuralgia do trigêmeo em uma menina de 17 anos de idade. Aveia petrosa superior foi relacionada ao conflito neurovascular, com resposta incomum para descompressão neurovascular eresolução completa dos sintomas no pós-operatório...


Trigeminal neuralgia in general is a disease of the elderly. Rarely, the disease presents during childhood. Therefore we sought toexplore the role of vascular compression in pediatric patients with medically refractory trigeminal neuralgia. A case of venouscompression related to trigeminal neuralgia is presented in a 17-year-old girl. Upper petrous vein was found to be related to aneurovascular conflict with unusual response to neurovascular decompression with complete resolution of symptoms in postoperativeperiod...


Asunto(s)
Humanos , Adolescente , Descompresión , Dolor Facial , Periodo Posoperatorio , Neuralgia del Trigémino , Venas
18.
Coluna/Columna ; 12(1): 70-72, 2013. tab
Artículo en Inglés | LILACS | ID: lil-673295

RESUMEN

Surgical experiments with laboratory animals are necessary for medical research. These studies aim to clarify the mechanism of disease, investigate the action and efficacy of new drugs or biological markers, as well as develop and enhance new therapies and apply new techniques. Regarding the models of spinal cord injury (SCI), there are several different methods that address the handling of the animals, especially concerning the use of analgesics, antibiotics and pre- and postoperative management. The lack of uniformity and standardization among the studies does not allow the understanding of the model of SCI or the proper handling of the paraplegic animals, hampering the adequate interpretation and comparison of results. The goal of this study is to establish a standard protocol on the handling of animals subjected to experimental models of SCI.


Experimentações cirúrgicas em nível laboratorial com o uso de animais são necessárias para o desenvolvimento da pesquisa médica. Estes estudos têm o objetivo de identificar o mecanismo das doenças, pesquisar a ação e eficácia de novos medicamentos ou marcadores biológicos, além de desenvolver e aprimorar novas terapêuticas. Em relação aos modelos experimentais relacionados à lesão raquimedular, há diversas metodologias descritas sobres o manejo desses animais, especialmente em relação ao uso de analgésicos, antibióticos e manejo pré e pós operatórios. Essa variedade metodológica resulta na falta de uniformidade e padronização entre os estudos, prejudicando a interpretação adequada e a comparação entre os resultados. Diante deste cenário, este estudo tem objetivo de estabelecer um protocolo padrão sobre o manejo dos ratos submetidos a modelos experimentais de trauma raquimedular.


La realización de experimentos quirúrgicos con animales de laboratorio son necesarios para la investigación médica. Estos estudios tienen por objeto aclarar el mecanismo de las enfermedades, investigar la acción de nuevos medicamentos y marcadores biológicos, así como desarrollar y mejorar nuevas terapias y aplicar nuevas técnicas. En cuanto a los modelos animales de lesión de la médula espinal (SCI), existen varios métodos diferentes que abordan el cuidado de estos animales, especialmente en relación con el uso de analgésicos, antibióticos y manejo pre y post operatorio. La falta de uniformidad y estandarización entre los estudios no permite la comprensión del modelo de SCI o el manejo adecuado del animal parapléjico, lo que dificulta la interpretación y comparación adecuada de los resultados. El objetivo de este estudio es establece un protocolo estándar de manejo de animales sometidos a modelos experimentales de SCI.


Asunto(s)
Animales , Cobayas , Ratas , Modelos Animales , Paraplejía , Traumatismos de la Médula Espinal , Investigación Biomédica , Animales de Laboratorio
19.
J. coloproctol. (Rio J., Impr.) ; 32(3): 304-307, July-Sept. 2012. ilus
Artículo en Inglés | LILACS | ID: lil-660618

RESUMEN

In the past, extrapulmonary tuberculosis affected approximately 70% of patients with advanced pulmonary tuberculosis. However, with the advent of highly effective therapy, intestinal tuberculosis has become rare - even more unusual in patients without immunodeficiency, HIV and pulmonary disease. The purpose of this study was to report the case of two patients diagnosed with intestinal tuberculosis and no immunodeficiency, HIV or lung disease. The first patient was diagnosed by colonoscopy performed in a mass located in the ileocecal region. After the tuberculosis treatment, the patient presented improvement regarding the mass and symptoms. The diagnosis of the second patient was achieved only with surgical resection of the lesion in proximal transverse colon. It is important for health professionals to know that intestinal tuberculosis should be considered as differential diagnosis of intestinal diseases, also for immunocompetent patients, even regarded as a rare disease. (AU)


No passado, a tuberculose extrapulmonar acometia cerca de 70% dos pacientes com tuberculose pulmonar avançada. Porém, com o surgimento da terapia de alta eficácia, a tuberculose intestinal tornou-se de ocorrência mais rara - sendo ainda mais incomum de ocorrer em pacientes sem imunodeficiência, HIV e doença pulmonar. O objetivo deste estudo foi apresentar o caso de dois pacientes diagnosticados com tuberculose intestinal, sem sinais de imunodeficiência, HIV ou doença pulmonar. A primeira paciente foi diagnosticada por meio de biópsias realizadas por colonoscopia em uma massa localizada em região ileocecal; após o tratamento da tuberculose a paciente apresentou melhora da lesão e dos sintomas. O diagnóstico do segundo paciente só foi obtido com a ressecção cirúrgica da lesão em cólon transverso proximal. É importante que os profissionais da saúde saibam que a tuberculose intestinal deve ser considerada como diagnóstico diferencial de patologias intestinais, até mesmo em pacientes imunocompetentes, mesmo sendo rara. (AU)


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Tuberculosis Gastrointestinal/diagnóstico , Colon/cirugía , Íleon/diagnóstico por imagen
20.
J. coloproctol. (Rio J., Impr.) ; 32(2): 144-147, Apr.-June 2012. graf, tab
Artículo en Inglés | LILACS | ID: lil-647831

RESUMEN

INTRODUCTION: Cancer is a disease that affects a large population, being the colorectal cancer one of the most prevalent. The early diagnosis of these neoplasms represents a better life expectancy. The high cost of diagnostic tests and the low socioeconomic status are considered factors leading to delayed diagnosis. OBJECTIVES: Assess the difference between colorectal cancer staging in patients of private clinics and patients of the Brazilian National Health Service (SUS) and assess the changes in cancer staging in the past five years. METHODS: This retrospective study was conducted with 53 patients divided in two groups (SUS and private clinic) diagnosed with colorectal cancer and treated in 2009. Staging of patients diagnosed in 2009 was compared with data from patients diagnosed in 2004, already published in 2005. RESULTS: Both groups were similar in gender and age. Regarding the staging of patients, no statistical difference was observed between the two groups (p=0.147). When comparing the staging of patients diagnosed in 2009 with that of patients studied in 2004, patients diagnosed in 2009 presented early stages (II and III) in relation to patients analyzed in 2004 (III and IV), p<0.001. CONCLUSION: No significant difference was observed in cancer staging between SUS and private clinic patients. The patients analyzed in 2009 were diagnosed with early stage tumors when compared to patients diagnosed in 2004. (AU)


INTRODUÇÃO: O câncer é uma doença que afeta grande parte da população, sendo o câncer colorretal um dos mais prevalentes. O diagnóstico precoce dessas neoplasias resulta em uma melhor expectativa de vida. O alto custo dos exames diagnósticos e o baixo nível socioeconômico são apontados como fatores que levam ao atraso no diagnóstico. OBJETIVOS: Avaliar a diferença no estadiamento de câncer colorretal no momento do diagnóstico de pacientes oriundos da clínica privada e pacientes do Sistema Único de Saúde (SUS), assim como, avaliar as mudanças no estadiamento nos últimos cinco anos. MÉTODOS: Estudo retrospectivo envolvendo 54 pacientes divididos em dois grupos (SUS e clínica privada) diagnosticados no ano de 2009. Os estadiamentos dos pacientes diagnosticados em 2009 foram comparados com os dados de pacientes diagnosticados em 2004, já publicados em 2005. RESULTADOS: Ambos os grupos eram similares em gênero e idade. Em relação ao estadiamento dos pacientes não houve diferença estatística entre os dois grupos (p=0,147). Na comparação entre os pacientes de 2009 e os pacientes estudados em 2004 se evidencia que os pacientes de 2009 apresentaram-se com estádios mais precoces (II e III) em relação aos pacientes de 2004 (III e IV), p<0,001. CONCLUSÃO: Não há diferença no estadiamento dos pacientes do SUS comparado ao estadiamento dos pacientes da clínica privada. Os pacientes tratados no ano de 2009 se apresentaram com estádios mais precoces em relação aos tratados em 2004. (AU)


Asunto(s)
Humanos , Masculino , Femenino , Persona de Mediana Edad , Neoplasias del Recto , Neoplasias del Colon , Estadificación de Neoplasias , Cobertura de Servicios Privados de Salud , Atención a la Salud
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